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Pentobarbital was used in a U.S. execution for the first time in December 2010 in Oklahoma, as Portion of a three-drug protocol.[16] In March 2011 pentobarbital was used for The 1st time as the only real drug inside of a U.S. execution, in Ohio. Since then a number of states plus the federal govt have utilised pentobarbital for lethal injections; s